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New gene-editing techniques could transform food crops – or die on the vine

Publication date: 01/03/2016

The CRISPR revolution may be having its most profound – and least publicized – effect in agriculture. By the fall of 2015 about 50 scientific papers had been published reporting uses of CRISPR in gene-edited plants, and there are preliminary signs that the U.S. Department of Agriculture, one of the agencies that assesses genetically modified agricultural products, does not think all gene-edited crops require the same regulatory attention as “traditional” genetically modified organisms, or GMOs. With that regulatory door even slightly ajar, companies are racing to get gene-edited crops into the fields and, ultimately, into the food supply.

Will consumers agree? Or will they see CRISPR crops as the latest iteration of Frankenfood—a genetic distortion of nature in which foreign (and agribusiness-friendly) DNA is muscled into a species, with unpredictable health or environmental consequences? Because CRISPR is only now being applied to food crops, the question has not yet surfaced for the public, but it will soon.

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Opinion: The complex nature of GMOs calls for a new conversation

Publication date: 07/10/2015

What are the conditions under which GMOs might work more effectively? Can they be compatible with the needs of farmers, eaters and their communities, not only with the aims of corporations and biotech scientists?

We can start by broadening the conversation around human health to include social science and natural science perspectives, and encompassing the ripple effects of technologies packaged with GMOs. we can open the floor to engaged citizens and laborers across the food system. We also need better regulatory oversight. We can bring GM research and development into the public sphere.

A nonreductionist evaluation of GMOs can push us toward thinking about effects at multiple scales and time spans. Such an evaluation can get us to think deeply about who benefits from technologies, who controls their availability and access, and who makes such decisions. We get to think about the entanglements of politics, the media and public interest in shaping scientific validity and “consensus.”

In short, we are invited to think socially and ecologically — indeed agroecologically — about the utility and value of engineered seeds. “If GMOs can survive such scrutiny and emerge as a beneficial tool, ” writes the author “I’m certainly not anti-GMO”.

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Conflicting values in the GM food crop debate

Publication date: 15/09/2015

The debate over GM food crops has been going on since the 1990s. The debate ranges over a wide spectrum of issues, which can be grouped under three main headings. First, and of most immediate concern, is the debate over the possible effect of GM foods on human health. Second is the debate over the impact of GM crops on the environment. And last is the socio-economic impact of GM agriculture.

This paper addresses the first debate, the possible health hazards of GM foods, and why it has not yet been resolved. The impact of GM crops on the environment is now well known – the rise and spread of “superweeds”, weeds resistant to herbicides, is well documented [1-3] and the engineering of resistance to even stronger herbicides is well underway with the US EPA approval of plant varieties that are tolerant of the herbicides 2,4-D [4] and approval imminent for the use of dicamba in Monsanto’s Roundup Ready XTend crop system [5].

The socio-economic debate is mainly concerned with the role of the agro-chemical industry in developing nations. This is still an open debate. On the one hand, critics of GM crops worry that the agrochemical industry will exploit the land and labour resources of developing nations, while advocates of GM crops believe that the technology can make a positive contribution to food production in these countries.

It is important to note that many advocates of GM crops are motivated by the possible benefits that GM technology may bring to humanity, and especially to the hungry people in the developing world. Other advocates, in the commercial world, are motivated by the profits that GM technology may bring to farmers and, of course, to their own industry.

This paper will provide a careful analysis of a debate over the safety of GM crops and food that took place in 1999, a debate that marks the turning point in popular attitude towards GM technology. The values underlying these two different sources of GM advocacy will be identified in that analysis. Their role in the shift from an open and reasoned debate over the science of GM to an ongoing, and often emotional, attempt to silence the critics of GM technology will be discussed. This will show how and why many advocates of GM are entirely opposed to any research that indicates possible hazards of GM crops and food.

Resource type: Adobe Acrobat (.pdf)

When science and citizens connect: public engagement on genetically modified organisms

Publication date: 07/07/2015

This report summarises the presentations and discussion of a 2 day workshop on January 15-16, 2015, in Washington, DC organised as part of the National Research Council’s Roundtable on Public Interfaces of the Life Sciences.

The aim was to to explore the public interfaces between scientists and citizens in the context of genetically engineered (GE) organisms. The workshop presentations and discussions dealt with perspectives on scientific engagement in a world where science is interpreted through a variety of lenses, including cultural values and political dispositions, and with strategies based on evidence in social science to improve public conversation about controversial topics in science. The workshop istelf focused on public perceptions and debates about genetically engineered plants and animals, commonly known as genetically modified organisms (GMOs), because the development and application of GMOs are heavily debated among some stakeholders, including scientists. For some applications of GMOs, the societal debate is so contentious that it can be difficult for members of the public, including policy-makers, to make decisions. Thus, although the workshop focused on issues related to public interfaces with the life science that apply to many science policy debates, the discussions are particularly relevant for anyone involved with the GMO debate.

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The construction of imaginaries of the public as a threat to synthetic biology

Publication date: 31/03/2015

Scientific institutions and innovation-focused government bodies have identified public attitudes to synthetic biology as an obstruction to the field. This view is based on a perception that the public is (or will likely become) fearful of synthetic biology and that a ‘public scare’ would impede development of the field.

Fear of the public’s fear of synthetic biology, which I characterise as ‘synbiophobia-phobia’, has been the driving force behind the promotion of public engagement and other activities to address ‘ethical, legal and social issues’ (ELSI).

These activities have been problematic in two ways. Firstly, they are based on the discredited ‘deficit-model’ understanding of public responses to science, in which negative public attitudes towards science are thought to result from a lack of scientific knowledge. Secondly, they have taken for granted sociotechnical expectations put forward by scientific institutions.

These promises of the field, and the tacit normative commitments embedded within them, have not been opened up to public appraisal. Synthetic biology’s ELSI-work has taken place early on, before commercialisation, but rather than helping to avoid a polarised controversy, this effort has laid the battleground for conflict among opposing groups when products begin to reach the market.

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The GMO quandary and what it means for social philosophy

Publication date: 13/06/2014

Agricultural crops developed using the tools of genetic engineering (so-called “GMOs”) have become socially institutionalized in three ways that substantially compromise the inherent potential of plant transformation tools.

The first is that when farming depends upon debt finance, farmers find themselves in a competitive situation such that efficiency-enhancing technology fuels a trend of bankruptcy and increasing scale of production. As efficiency increasing tools, GMOs are embedded in controversial processes of social change in rural economies. The United States, at least, has chosen not to undertake policy interventions to slow or reverse this trend.

The second institutionalization of GMOs is found in the way that agricultural science has become divided between two camps, one focused on efficiency and total global production, the other focused on maintaining soil and water ecosystems in the face of both population growth and climate change. GMOs have been strongly supported by the first camp and regarded as irrelevant (at best) to the goals of the second.

Finally, GMOs have become symbolic markers in the global debate over neoliberal institutions for trade and the protection of intellectual property. While there may be agronomic arguments for favoring GMO technology, the way that it has become situated in each of these social debates insures that it will be subject to strong opposition without regard to its biological risks and potential benefits.

Resource type: Adobe Acrobat (.pdf)

Ethics debates on food technologies in the three regions of Europe, India and China

Publication date: 28/02/2014

The use of technology and innovation in developing long-term global food security, and ensuring sustainable and adequate food production, is contextualized by values and controversies associated with food technologies. The framing and context of these technologies may impact on consumer perceptions and acceptance.

In some countries this can influence policy decisions. Analysis of the public discourses on the themes of innovationriskpower and control, and their socio-economic and ethical implications, is applied to explain the utility of novel and emerging food technologies. Potential differences in stakeholder interests are taken into account in different economic and regulatory environments, contrasting Europe with the emerging economies of China and India.

In the case of India, there is considerable public debate on finding a balance between various technological choices for food production, viz transgenic, traditional breeding and organic production. In China, the debate about technological innovation is driven largely by political and scientific elites with relatively little consumer debate. European agri-technological innovation is framed by ‘post-productivism’, which informs both implementation strategies and regulatory and governance issues. Economic values cannot be dismissed as irrelevant to the European innovation process, in particular in relation to investment and scientific endeavour.

This report by Global Ethics in Science and Technology (GEST) aims to identify the nature of ethical debates on food technologies in Europe, India and China and to compare how these are addressed by stakeholders in the different regions. It highlights how ethical issues reach the public and political agenda in the area of food; how and to what extent food ethics is incorporated into official government decision-making structures; how other actors or stakeholders including regulators, innovators, producers, consumers etc., deal with ethical issues related to food technology together with any structures or processes implemented to promote public trust.

Resource type: Adobe Acrobat (.pdf)

SynBio politics: bringing synthetic biology into debate

Publication date: 18/02/2014

Synthetic biology (SynBio) raises a lot of interest in its potential applications and a lot of questions about risk, ownership and society’s relationship with nature.

In scientific circles, the process of opinion making around SynBio in full swing. However, as this report argues, this process also calls for engagement from society. Synthetic biology offers potential for novel drugs and vaccines, as well as for ‘greener’ chemicals and biofuels.

Nonetheless, this field also brings with it various challenges, ranging from regulatory issues of biosafety, biosecurity and intellectual property rights to potential environmental and socioeconomic risks and related ethical questions. It is thus essential to establish an open dialogue between stakeholders, including the public, concerning the technology’s potential benefits and risks and to explore possibilities for ‘collaborative shaping’ of the field.

This report published by the Dutch Rathenau Instituut summarises the Meeting of Young Minds, a 2011 meeting of ‘politicians of the future’ – representing Dutch Political outh Organizations, organised by the Rathenau Instituut and focused on the issue of SynBio.  Althoug,h originally published as a contribution to the Dutch debate, it also has relevance for the discussion in Europe and internationally.

Resource type: Adobe Acrobat (.pdf)

Ethics debates on food technologies in the EU

Publication date: 31/07/2013

Food is essential for human life and existence. Therefore production of food sufficient to feed the global population in a manner that is sustainable both now and for future generations is essential. For centuries agricultural production was conducted utilising ecologically sustainable agricultural processes. This model still operates in a number of developing countries (in for example, SE Asia, South America and sub-Saharan Africa), but in most of the developed world, there was a move to a productivist model of intensive farming, during the 20th century.

The objective of intensified agriculture is increased levels of production, specialisation and expansion through the use of convergent application of biotechnology (including genetics), nanotechnology and information technology.  Lowe et al  have defined productivism as “a commitment to an intensive, industrially driven and expansionist agriculture with state support based primarily on output and increased productivity”. The consequent environmental damage caused by intensive farming methods has led to the emergence of an alternative, a post-productivist model with the focus shifting from intensive farming to shorter food supply chains, better added value for farmers and more sustainable, environmentally friendly, localised and pluralistic agricultural practices.

Whereas the key stakeholders in the productivist model tend to be farmers, the food industry and policy makers, the stakeholder community of the post-productivist model is much wider and includes in addition to producers, distributers and policy makers, local rural and urban communities, environmentalists, consumers, NGOs, special interest groups and
others, with less emphasis on commodity production, and a greater focus on shorter less intense farming, reducing environmental damage, animal welfare and a shift towards
sustainable agriculture and conservation or restoration of valued landscapes and habitats. An important manifestation of this approach has been a change in consumer awareness, behaviour and engagement with the whole of the food chain from “gate to plate” with particular emphasis on perceptions of risk, precaution, “naturalness” and animal welfare, driven to a not inconsiderable extent by a number of high profile health scares particularly across the European market. This has resulted in the development of new market relationships with a consumer driven focus.

At the same time the productivist approach to food production has been moving towards a more agri-industrial model. This industrial model of agriculture depends on further increasing specialisation and homogeneous production, with production control and pricing shifting from primary producers (farmers) to highly competitive industrial distributors and highly industrialised multinational chemical, biological and pharmaceutical companies implementing global value chains. This results in a squeeze on the prices paid to farmers by distributors and an increasing pressure for a more intensive production dependent on external inputs of water and energy together with patented, product specific, fertilizer and pesticides and increasingly, the use of scientific research to modify, control and maintain reproduction of crops and animals.

In recent years Europe has been the focus of a number of high profile food-related issues or concerns which have had a significant impact on consumer confidence and which have
resulted in large changes to the European regulatory structure with important consequences for the development, regulation, economics and politics of the agri-industry.

One consequence of these events has been a huge loss of confidence by consumers in the food industry and also in food regulators, and this has been accompanied by strong
consumer demand for much greater consultation and input into all stages of the food chain and its regulation. These high levels of consumer sensitivity and much tighter coordinated regulation as a result of loss of consumer trust, has been an important factor in increasing support for the post-productivist model of food and agriculture in Europe.

This is in stark contrast to the situation which exists in the US, where food and agriculture are regulated by the FDA, a body more remote from the US consumer. Much has been written about the confidence and trust of the American consumer in national institutional arrangements and it has proved much easier in such an environment to introduce innovations such as products and processes based on GM technology, which has been much more problematic in Europe.

As a result the US still remains much closer to the agri-industrial model. These two agri-food production models now contend in the policy and economic fields for a dominant role in food production and supply to consumers. Both approaches are dependent on continuous scientific innovation in order to develop and maintain competitive advantage.

While to some extent the consumer is over a barrel as they are dependent on what is available, i.e. what is provided by producers and distributers, they do have the ability to “vote with their feet” and can and do reject products in which they have little or no confidence. Therefore failure to recognise and respond to consumer preferences and concerns may generate consumer protest and shifting of loyalties to different production systems. Hence the acceptance and trust of the consumer is important for economic viability and it is essential for both models to be able to secure positive attitudes in consumer perceptions of risk and ethical values in relation to methods of production, processing, packaging and distribution. Effective regulation is a key element in securing consumer trust and hence confidence in both products and processes.

This report from Global Ethics in Science and Technology (GEST) considers these two agri-food models in relation to innovation, risk and power and control issues together with the associated ethical issues and consumer perceptions.

Resource type: Adobe Acrobat (.pdf)

Biotechnology as seen by Quakers: moral vision, ethical assessment and action

Publication date: 30/06/2011
Biotechnology brings up differing perspectives on science, cosmology, and on life itself and the human role in Creation (or the world, depending on one’s theology). These are important discussions for members of a faith community, but do we need to seek unity concerning them?
One of Quakerism’s characteristics is an avoidance of creedal rigidity in favour of openness to inquiry and lived experience. The resulting diversity is a source of spiritual nourishment that most Friends cherish. This is especially the case for the large philosophical and theological questions that biotechnology raises. And while some Friends may feel that certain issues have such significant implications that these become the heart of the matter for them, the wellspring for practical concern needn’t be the same for everyone. There is still room for consensus about specific issues and action to address them.
Three basic questions emerge on this issue:
  • What spiritual groundings does biotechnology, in its many applications, touch on, and do Friends need to be in agreement about these matters?
  • How should Friends go about assessing biotechnology’s ethical and moral implications?
  • If moved to take action, what could Friends do about biotechnology’s direction and management?
This 2011 fact sheet has been prepared by the Canadian Institute for Environmental Law and Policy (CIELAP) for Quaker Institute for the Future (QIF) has been developed to help Quakers and others in faith traditions to reflect and act on concerns about biotechnology.

 

Resource type: Adobe Acrobat (.pdf)