This report argues that releasing genetically modified micro-organisms (GMMs) into the environment poses unpredictable risks to human health. Microbes evolve fast, exchange genes and spread between people, so even a small edit could make a beneficial microbe harmful or, at worst, spark an outbreak. The briefing says the EU’s proposed fast-track approval procedure is inadequate. It would prioritise GM versions of common food and probiotic microbes, rely on a flawed “genes of concern” screen, and weaken the risk assessment, monitoring and liability safeguards in current law (Directive 2001/18/EC). It would also hand the European Commission unaccountable powers. With almost no market for openly released GMMs, and a risk of harming non-GM sectors, the authors call for the fast-track to be scrapped and for GMMs to stay in contained use.