Publication date: 21/10/2021

Summary

This review examines the use of site-directed nuclease 1 (SDN-1) technology in crop plants, which enables precise genetic changes for market-oriented traits but raises regulatory and safety concerns. SDN-1 can create both simple and complex genomic alterations, some comparable to those from natural mutations or conventional breeding. However, analysis shows that nearly half of SDN-1-modified plants exhibit complex genomic changes that could pose new risks. The study emphasizes the need for case-specific risk assessments that consider both the modification process and the final product, to ensure the safety of humans, animals, and the environment under evolving genomic technologies.

Resource type: article: Web Page